FATE-MAPPING AND FUNCTIONAL DISSECTION REVEAL PERILOUS INFLUENCE OF TYPE I INTERFERON SIGNALING IN MOUSE BRAIN AGING

Fate-mapping and functional dissection reveal perilous influence of type I interferon signaling in mouse brain aging

Abstract Background Aging significantly elevates the risk of developing neurodegenerative diseases.Neuroinflammation is a universal hallmark of neurodegeneration as well as normal brain aging.Which branches of age-related neuroinflammation, and how they precondition the brain toward pathological progression, remain ill-understood.The presence of el

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First report of recurrent parthenogenesis as an adaptive reproductive strategy in the endangered common smooth-hound shark Mustelus mustelus

Abstract Parthenogenesis, or virgin birth, describes a mode of reproduction where an egg develops into an offspring without fertilization, and is observed across various vertebrate taxa, excluding mammals.Obligate parthenogenesis, found in around 100 vertebrate species and 1000 invertebrate species, is relatively rare.Conversely, facultative parthe

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China’s Urban and Rural Development Significantly Affects the Pattern of Human Appropriation of Net Primary Production

Increasing human activities have greatly influenced the ecosystem and the use of ecological resources, and the unbalanced urban–rural development in China Nutritional Yeast (urban and rural areas being two major bases of human activities) has always been accompanied by heterogeneous ecological effects.Human appropriation of net primary production

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Intergenerational Perspectives on Media and Fake News During Covid-19: Results From Online Intergenerational Focus Groups

This article reflects on intergenerational perspectives on media Glass Pumpkin habits and fake news during Covid-19.Active participation is closely linked to the citizens’ media literacy competencies.Due to the Covid-19 pandemic, inequalities in access, use, and understanding of the information conveyed by the media became more evident.Digital sk

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The Economic-Financial Crime of the 21st Century

Economic-financial crime generates major damage to ONE CHOCOLATE national economies, the EU budget and globally.In recent years, the fight against this vast and complex phenomenon has been intensified, developing methods of combating, investigating and sanctioning the forms of manifestation of the economic-financial crime.At the international level

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